Matt McIlwain

I’m a Managing Director at Madrona, where I partner with founders building enduring, software-driven companies.

I’ve been investing for over 25 years across major technology shifts, from the internet and SaaS to cloud and now AI. I’ve partnered with companies like Apptio, Isilon, Smartsheet, Accolade, Turi, ExtraHop, and OctoML, and currently work with teams at Amperity, Read AI, MotherDuck, EdgeRunner AI, A-Alpha Bio, and Synthesize Bio.

I focus on enterprise software, AI-driven applications, and areas where innovation intersects.